This study was conducted to evaluate the effect of substitution of fish meal with poultry waste byproducts in the diet of gold severum (Cichlasoma severum). In this regard, four experimental groups, each with three replicates, introduced and specimens being reared for 93 days. Four diets contain different levels of poultry by-product meal (25, 50, 75 percentages of fish meal were being replaced). 144 Severum juveniles with an average initial weight of (1/39±0/17) and initial length (1/15±0/71) were stocked 12 aquariums, specimens were fed every six hours a day and biometry conducted every fourteen days. At the end of the 97 days, the results were being analyzed by use of one- way ANOVA routine and growth performance indices and FCR revealed that the replacement of 50 percent of fish meal with poultry by-product meal significantly impact the gold severum and shows that this ingredient could be used effectively in fish feed formulation process.